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I would probably focus my research on psychological articles and use those to analyze the characters myself. I don't know what I would find, exactly, seeing as I'm not well-versed in the science of psychiatry, but it would be cool to be able to come up with my own conclusions about how, why, and when Macbeth and Lady Macbeth changed. It would be interesting to see what effect witches would have had on their mental state, how the lure of power might have pushed them over the edge, and perhaps what supporting characters such as Banquo or Macduff would have contributed to their changes. I think I would try to avoid articles already written about the mental state and character changes of Macbeth and his wife in order to try and formulate my own argument and not be heavily influenced by the arguments of scholars past and present. I'm sure there is so much that has been written on this subject before, so in order to keep it somewhat original, I would do my best to stay away from those articles.